Norovirus Regulation of the Innate Immune Response and Apoptosis Occurs via the Product of the Alternative Open Reading Frame 4

Small RNA viruses have evolved many mechanisms to increase the capacity of their short genomes. Here we describe the identification and characterization of a novel open reading frame (ORF4) encoded by the murine norovirus (MNV) subgenomic RNA, in an alternative reading frame overlapping the VP1 codi...

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Autors principals: McFadden, Nora, Bailey, Dalan, Carrara, Guia, Benson, Alicia, Chaudhry, Yasmin, Shortland, Amita, Heeney, Jonathan, Yarovinsky, Felix, Simmonds, Peter, Macdonald, Andrew, Goodfellow, Ian
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234229/
https://ncbi.nlm.nih.gov/pubmed/22174679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002413
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