Influence of genome-scale RNA structure disruption on the replication of murine norovirus—similar replication kinetics in cell culture but attenuation of viral fitness in vivo

Mechanisms by which certain RNA viruses, such as hepatitis C virus, establish persistent infections and cause chronic disease are of fundamental importance in viral pathogenesis. Mammalian positive-stranded RNA viruses establishing persistence typically possess genome-scale ordered RNA secondary str...

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Detalhes bibliográficos
Main Authors: McFadden, Nora, Arias, Armando, Dry, Inga, Bailey, Dalan, Witteveldt, Jeroen, Evans, David J., Goodfellow, Ian, Simmonds, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695492/
https://ncbi.nlm.nih.gov/pubmed/23630317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt334
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