Structural Insights into the Inhibition of Cytosolic 5′-Nucleotidase II (cN-II) by Ribonucleoside 5′-Monophosphate Analogues

Cytosolic 5′-nucleotidase II (cN-II) regulates the intracellular nucleotide pools within the cell by catalyzing the dephosphorylation of 6-hydroxypurine nucleoside 5′-monophosphates. Beside this physiological function, high level of cN-II expression is correlated with abnormal patient outcome when t...

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Detalhes bibliográficos
Main Authors: Gallier, Franck, Lallemand, Perrine, Meurillon, Maïa, Jordheim, Lars P., Dumontet, Charles, Périgaud, Christian, Lionne, Corinne, Peyrottes, Suzanne, Chaloin, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234209/
https://ncbi.nlm.nih.gov/pubmed/22174667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002295
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