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Azelnidipine prevents cardiac dysfunction in streptozotocin-diabetic rats by reducing intracellular calcium accumulation, oxidative stress and apoptosis

BACKGROUND: Numerous evidences suggest that diabetic heart is characterized by compromised ventricular contraction and prolonged relaxation attributable to multiple causative factors including calcium accumulation, oxidative stress and apoptosis. Therapeutic interventions to prevent calcium accumula...

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Hlavní autoři: Kain, Vasundhara, Kumar, Sandeep, Sitasawad, Sandhya L
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234183/
https://ncbi.nlm.nih.gov/pubmed/22054019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-10-97
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