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Maspin is a deoxycholate-inducible, anti-apoptotic stress-response protein differentially expressed during colon carcinogenesis

Increased maspin expression in the colon is related to colon cancer risk and patient survival. Maspin is induced by the hydrophobic bile acid, deoxycholate (DOC), which is an endogenous carcinogen and inducer of oxidative stress and DNA damage in the colon. Persistent exposure of colon epithelial ce...

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Detalhes bibliográficos
Main Authors: Payne, Claire M, Holubec, Hana, Crowley-Skillicorn, Cheray, Nguyen, Huy, Bernstein, Harris, Wilcox, George, Bernstein, Carol
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234125/
https://ncbi.nlm.nih.gov/pubmed/22162927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CEG.S24093
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