Cigarette smoke causes lung vascular barrier dysfunction via oxidative stress-mediated inhibition of RhoA and focal adhesion kinase

Cigarette smoke (CS) is a major cause of chronic lung and cardiovascular diseases. Recent studies indicate that tobacco use is also a risk factor for acute lung injury (ALI) associated with blunt trauma. Increased endothelial cell (EC) permeability is a hallmark of ALI. CS increases EC permeability...

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Detalhes bibliográficos
Main Authors: Lu, Qing, Sakhatskyy, Pavlo, Grinnell, Katie, Newton, Julie, Ortiz, Melanie, Wang, Yulian, Sanchez-Esteban, Juan, Harrington, Elizabeth O., Rounds, Sharon
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Call for Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233834/
https://ncbi.nlm.nih.gov/pubmed/21984567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00178.2011
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