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Activation of hypoxia-inducible factor-1 protects airway epithelium against oxidant-induced barrier dysfunction

The respiratory epithelium forms an important barrier against inhaled pollutants and microorganisms, and its barrier function is often compromised during inflammatory airway diseases. Epithelial activation of hypoxia-inducible factor-1 (HIF-1) represents one feature of airway inflammation, but the f...

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Detalhes bibliográficos
Main Authors: Olson, Nels, Hristova, Milena, Heintz, Nicholas H., Lounsbury, Karen M., van der Vliet, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233830/
https://ncbi.nlm.nih.gov/pubmed/21926263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00250.2011
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