Hypoxia-Inducible Factor-1α Regulates CD55 in Airway Epithelium

Airway epithelial CD55 down-regulation occurs in several hypoxia-associated pulmonary diseases, but the mechanism is unknown. Using in vivo and in vitro assays of pharmacologic inhibition and gene silencing, the current study investigated the role of hypoxia-inducible factor (HIF)-1α in regulating a...

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Publicado en:Am J Respir Cell Mol Biol
Autores principales: Pandya, Pankita H., Fisher, Amanda J., Mickler, Elizabeth A., Temm, Constance J., Lipking, Kelsey P., Gracon, Adam, Rothhaar, Katia, Sandusky, George E., Murray, Mary, Pollok, Karen, Renbarger, Jamie, Blum, Janice S., Lahm, Tim, Wilkes, David S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Thoracic Society 2016
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248950/
https://ncbi.nlm.nih.gov/pubmed/27494303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0237OC
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