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Inhibitors of protein and RNA synthesis cause a rapid block in prostaglandin production at the prostaglandin synthase step.

Inhibitors of protein or RNA synthesis prevented prostaglandin (PG) production in isolated skeletal muscles, brain, and spleen. Incubation of rat muscles with cycloheximide prevented the stimulation of PGE2 production induced in vitro by the Ca2+ ionophore A23187 and in vivo by injection of endotoxi...

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Detalhes bibliográficos
Main Authors: Fagan, J M, Goldberg, A L
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC323383/
https://ncbi.nlm.nih.gov/pubmed/3085105
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