ATP: a mediator for HCl-induced TRPV1 activation in esophageal mucosa

In esophageal mucosa, HCl causes TRPV1-mediated release of calcitonin gene-related peptide (CGRP) and substance P (SP) from submucosal neurons and of platelet-activating factor (PAF) from epithelial cells. CGRP and SP release was unaffected by PAF antagonists but reduced by the purinergic antagonist...

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Autors principals: Ma, Jie, Altomare, Annamaria, Rieder, Florian, Behar, Jose, Biancani, Piero, Harnett, Karen M.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2011
Matèries:
Neuroregulation and Motility
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233789/
https://ncbi.nlm.nih.gov/pubmed/21960521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00336.2011
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