Promyelocytic leukemia inhibits adipogenesis, and loss of promyelocytic leukemia results in fat accumulation in mice

The function of the tumor suppressor promyelocytic leukemia (PML) protein is disrupted in promyelocytic leukemia. PML has been reported to function as a negative regulator of mTOR (mammalian target of rapamycin) and nuclear Akt under some conditions. mTOR and Akt pathways regulate a diverse array of...

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Detalhes bibliográficos
Main Authors: Kim, Myung K., Yang, Shutong, Lee, Kyoung-Hwa, Um, Jee-Hyun, Liu, Mengyang, Kang, Hyeog, Park, Sung Jun, Chung, Jay H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233778/
https://ncbi.nlm.nih.gov/pubmed/21846906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00092.2011
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