AMP-Activated Protein Kinase–Deficient Mice Are Resistant to the Metabolic Effects of Resveratrol

OBJECTIVE: Resveratrol, a natural polyphenolic compound that is found in grapes and red wine, increases metabolic rate, insulin sensitivity, mitochondrial biogenesis, and physical endurance and reduces fat accumulation in mice. Although it is thought that resveratrol targets Sirt1, this is controver...

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Detalhes bibliográficos
Main Authors: Um, Jee-Hyun, Park, Sung-Jun, Kang, Hyeog, Yang, Shutong, Foretz, Marc, McBurney, Michael W., Kim, Myung K., Viollet, Benoit, Chung, Jay H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828647/
https://ncbi.nlm.nih.gov/pubmed/19934007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0482
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