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Hyperglucagonemia precedes a decline in insulin secretion and causes hyperglycemia in chronically glucose-infused rats

Islet damage from glucose toxicity is implicated in the pathogenesis of type 2 diabetes, but the sequence of events leading to islet cell dysfunction and hyperglycemia remains unclear. To examine the early stages of islet pathology resulting from increased basal glucose loads, normal awake rats were...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Jamison, Rachel A., Stark, Romana, Dong, Jianying, Yonemitsu, Shin, Zhang, Dongyan, Shulman, Gerald I., Kibbey, Richard G.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Physiological Society 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233775/
https://ncbi.nlm.nih.gov/pubmed/21862723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00175.2011
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