A DNA insertion/deletion necessitates an aberrant RNA splice accounting for a mu heavy chain disease protein.

The human heavy chain disease protein BW is an immunoglobulin mu-chain variant whose amino terminus is initiated at the fifth amino acid of the first constant region domain. We cloned and analyzed both rearranged heavy chain alleles from BW leukemic cells to determine the molecular basis for this de...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Bakhshi, A, Guglielmi, P, Siebenlist, U, Ravetch, J V, Jensen, J P, Korsmeyer, S J
Format: Artigo
Sprog:Inglês
Udgivet: 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC323365/
https://ncbi.nlm.nih.gov/pubmed/3085103
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker