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CD84 negatively regulates IgE high affinity receptor signaling in human mast cells

CD84 is a self-binding receptor from the CD150 family that is broadly expressed in hematopoietic cells. It has been described that the adaptors SAP and EAT-2 are critical for CD150 family members signaling and function. We observed that human mast cells express CD84 but lack SAP or EAT-2, that CD84...

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Detalhes bibliográficos
Main Authors: Álvarez-Errico, Damiana, Oliver-Vila, Irene, Aínsua-Enrich, Erola, Gilfillan, Alasdair M., Picado, César, Sayós, Joan, Martín, Margarita
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233232/
https://ncbi.nlm.nih.gov/pubmed/22068234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101626
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