Induction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor beta: a proposed model for indirect mitogenesis involving autocrine activity.

Treatment of quiescent cultures of mouse embryo-derived AKR-2B cells with transforming growth factor beta resulted in an early induction of c-sis mRNA. The increase in c-sis mRNA was followed by a corresponding increase in protein similar to platelet-derived growth factor (PDGF) in the culture mediu...

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Main Authors: Leof, E B, Proper, J A, Goustin, A S, Shipley, G D, DiCorleto, P E, Moses, H L
Format: Artigo
Jezik:Inglês
Izdano: 1986
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC323316/
https://ncbi.nlm.nih.gov/pubmed/3010310
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