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Vaginal Langerhans Cells Nonproductively Transporting HIV-1 Mediate Infection of T Cells

Although implied by other models, proof that Langerhans cells (LCs) in the human vagina participate in dissemination of infectious human immunodeficiency virus type 1 (HIV-1) has been lacking. Here, we show that LCs migrate from HIV-1-exposed vaginal epithelia and pass infectious virus to CD4(+) T c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ballweber, Lamar, Robinson, Barry, Kreger, Allison, Fialkow, Michael, Lentz, Gretchen, McElrath, M. Juliana, Hladik, Florian
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233146/
https://ncbi.nlm.nih.gov/pubmed/21976645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05615-11
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