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Molecular structure of the G.A base pair in DNA and its implications for the mechanism of transversion mutations.

The synthetic deoxydodecamer d(C-G-C-G-A-A-T-T-A-G-C-G) was analyzed by x-ray diffraction methods, and the structure was refined to a residual error of R = 0.17 at 2.5-A resolution (2 sigma data) with 83 water molecules located. The sequence crystallizes as a full turn of a B-DNA helix and contains...

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Main Authors: Brown, T, Hunter, W N, Kneale, G, Kennard, O
格式: Artigo
語言:Inglês
出版: 1986
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC323305/
https://ncbi.nlm.nih.gov/pubmed/3458205
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