Molecular structure of the G.A base pair in DNA and its implications for the mechanism of transversion mutations.
The synthetic deoxydodecamer d(C-G-C-G-A-A-T-T-A-G-C-G) was analyzed by x-ray diffraction methods, and the structure was refined to a residual error of R = 0.17 at 2.5-A resolution (2 sigma data) with 83 water molecules located. The sequence crystallizes as a full turn of a B-DNA helix and contains...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1986
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323305/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3458205/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.8.2402 |
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