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Ligand-Independent Phosphorylation of the Glucocorticoid Receptor Integrates Cellular Stress Pathways with Nuclear Receptor Signaling

Glucocorticoids are stress hormones that maintain homeostasis through gene regulation mediated by nuclear receptors. We have discovered that other cellular stressors are integrated with glucocorticoid signaling through a new hormone-independent phosphorylation site, Ser134, on the human glucocortico...

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Hlavní autoři: Galliher-Beckley, Amy Jo, Williams, Jason Grant, Cidlowski, John Anthony
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232926/
https://ncbi.nlm.nih.gov/pubmed/21930780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05866-11
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