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Harvey ras genes transform without mutant codons, apparently activated by truncation of a 5' exon (exon -1).

The hypothesis is tested that the ras gene of Harvey sarcoma virus (Ha-SV) and the proto-ras DNAs from certain tumor cells derive transforming function from specific codons in which they differ from normal proto-ras genes. Molecularly cloned Harvey proviral vectors carrying viral ras, normal rat pro...

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Autores principales: Cichutek, K, Duesberg, P H
Formato: Artigo
Lenguaje:Inglês
Publicado: 1986
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC323292/
https://ncbi.nlm.nih.gov/pubmed/3517865
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