Harvey ras genes transform without mutant codons, apparently activated by truncation of a 5' exon (exon -1).
The hypothesis is tested that the ras gene of Harvey sarcoma virus (Ha-SV) and the proto-ras DNAs from certain tumor cells derive transforming function from specific codons in which they differ from normal proto-ras genes. Molecularly cloned Harvey proviral vectors carrying viral ras, normal rat pro...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1986
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323292/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3517865/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.8.2340 |
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