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Role of the MexEF-OprN Efflux System in Low-Level Resistance of Pseudomonas aeruginosa to Ciprofloxacin

In this study, we investigated the resistance mechanisms to fluoroquinolones of 85 non-cystic fibrosis strains of Pseudomonas aeruginosa exhibiting a reduced susceptibility to ciprofloxacin (MICs from 0.25 to 2 μg/ml). In addition to MexAB-OprM (31 of 85 isolates) and MexXY/OprM (39 of 85), the MexE...

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Détails bibliographiques
Auteurs principaux: Llanes, Catherine, Köhler, Thilo, Patry, Isabelle, Dehecq, Barbara, van Delden, Christian, Plésiat, Patrick
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232816/
https://ncbi.nlm.nih.gov/pubmed/21911574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00101-11
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