Relationship between Vancomycin Trough Concentrations and Nephrotoxicity: a Prospective Multicenter Trial

Several single-center studies have suggested that higher doses of vancomycin, aimed at producing trough concentrations of >15 mg/liter, are associated with increased risk of nephrotoxicity. We prospectively assessed the relative incidence of nephrotoxicity in relation to trough concentration in p...

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Bibliografiske detaljer
Main Authors: Bosso, John A., Nappi, Jean, Rudisill, Celeste, Wellein, Marlea, Bookstaver, P. Brandon, Swindler, Jenna, Mauldin, Patrick D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232787/
https://ncbi.nlm.nih.gov/pubmed/21947388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00168-11
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