Pharmacokinetics and Safety of Single and Multiple Doses of ACHN-490 Injection Administered Intravenously in Healthy Subjects

ACHN-490 is an aminoglycoside with activity against multidrug-resistant pathogens, including those resistant to currently used aminoglycosides. Two randomized, double-blind, placebo-controlled clinical studies investigated the pharmacokinetics (PK), safety, and tolerability of ACHN-490 injection in...

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Autori principali: Cass, Robert T., Brooks, Carter D., Havrilla, Nancy A., Tack, Kenneth J., Borin, Marie T., Young, Don, Bruss, Jon B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2011
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232771/
https://ncbi.nlm.nih.gov/pubmed/21911572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00624-11
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