Efficacy of a New Fluoroquinolone, JNJ-Q2, in Murine Models of Staphylococcus aureus and Streptococcus pneumoniae Skin, Respiratory, and Systemic Infections

The in vivo efficacy of JNJ-Q2, a new broad-spectrum fluoroquinolone (FQ), was evaluated in a murine septicemia model with methicillin-susceptible Staphylococcus aureus (MSSA) and methicillin-resistant S. aureus (MRSA) and in a Streptococcus pneumoniae lower respiratory tract infection model. JNJ-Q2...

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Autores principales: Fernandez, Jeffrey, Hilliard, Jamese J., Morrow, Brian J., Melton, John L., Flamm, Robert K., Barron, Alfred M., Lynch, A. Simon
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2011
Materias:
Experimental Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232747/
https://ncbi.nlm.nih.gov/pubmed/21911568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00471-11
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