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Development of a Human-Murine Chimeric Immunoglobulin M for Use in the Serological Detection of Human Alphavirus Antibodies

Diagnosis of human alphaviral infections relies on serological techniques, such as the immunoglobulin M antibody capture–enzyme-linked immunosorbent assay (MAC-ELISA). We have humanized the alphavirus broadly cross-reactive murine monoclonal antibody 1A4B-6 to create a reagent capable of replacing h...

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Detalhes bibliográficos
Main Authors: Thibodeaux, Brett A., Liss, Nathan M., Panella, Amanda N., Roehrig, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232697/
https://ncbi.nlm.nih.gov/pubmed/21976225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.05269-11
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