Palmitoylation State Impacts Induction of Innate and Acquired Immunity by the Salmonella enterica Serovar Typhimurium msbB Mutant

Lipopolysaccharide (LPS), composed of lipid A, core, and O-antigen, is a major virulence factor of Salmonella enterica serovar Typhimurium, with lipid A being a major stimulator to induce the proinflammatory response via the Toll-like receptor 4 (TLR4)-MD2-CD14 pathway. While Salmonella msbB mutants...

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Hlavní autoři: Kong, Qingke, Six, David A., Liu, Qing, Gu, Lillian, Roland, Kenneth L., Raetz, Christian R. H., Curtiss, Roy
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232669/
https://ncbi.nlm.nih.gov/pubmed/21930761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05524-11
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