Interleukin-10 Alters Effector Functions of Multiple Genes Induced by Borrelia burgdorferi in Macrophages To Regulate Lyme Disease Inflammation

Interleukin-10 (IL-10) modulates inflammatory responses elicited in vitro and in vivo by Borrelia burgdorferi, the Lyme disease spirochete. How IL-10 modulates these inflammatory responses still remains elusive. We hypothesize that IL-10 inhibits effector functions of multiple genes induced by B. bu...

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Detalhes bibliográficos
Main Authors: Gautam, Aarti, Dixit, Saurabh, Philipp, Mario T., Singh, Shree R., Morici, Lisa A., Kaushal, Deepak, Dennis, Vida A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232652/
https://ncbi.nlm.nih.gov/pubmed/21947773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05451-11
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