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Autocrine and Exocrine Regulation of Interleukin-10 Production in THP-1 Cells Stimulated with Borrelia burgdorferi Lipoproteins

We have recently demonstrated that interleukin-10 (IL-10), produced by THP-1 monocytes in response to Borrelia burgdorferi lipoproteins, dampens the production of concomitantly elicited inflammatory cytokines. Thus, IL-10 could potentially down-regulate inflammatory and microbicidal effector mechani...

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Detalhes bibliográficos
Main Authors: Giambartolomei, Guillermo H., Dennis, Vida A., Lasater, Barbara L., Murthy, P. K., Philipp, Mario T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127882/
https://ncbi.nlm.nih.gov/pubmed/11895951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.4.1881-1888.2002
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