Cathepsin G and Neutrophil Elastase Play Critical and Nonredundant Roles in Lung-Protective Immunity against Streptococcus pneumoniae in Mice

Neutrophil serine proteases cathepsin G (CG), neutrophil elastase (NE), and proteinase 3 (PR3) have recently been shown to contribute to killing of Streptococcus pneumoniae in vitro. However, their relevance in lung-protective immunity against different serotypes of S. pneumoniae in vivo has not bee...

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Bibliographic Details
Main Authors: Hahn, Ines, Klaus, Anna, Janze, Ann-Kathrin, Steinwede, Kathrin, Ding, Nadine, Bohling, Jennifer, Brumshagen, Christina, Serrano, Hélène, Gauthier, Francis, Paton, James C., Welte, Tobias, Maus, Ulrich A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232647/
https://ncbi.nlm.nih.gov/pubmed/21911460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05593-11
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