Leukotrienes C4 and D4 stimulate human endothelial cells to synthesize platelet-activating factor and bind neutrophils.
Human endothelial cells in culture produced platelet-activating factor (PAF; 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) when stimulated with leukotriene C4 or D4 (LTC4 or LTD4). Other arachidonate metabolites did not induce the synthesis of PAF. Accumulation of PAF was a prolonged response with...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1986
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323260/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3457383/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.7.2204 |
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