Origin of eukaryotic introns: a hypothesis, based on codon distribution statistics in genes, and its implications.
A hypothesis for the origin of introns in eukaryotic genes is developed. By computer simulation it was found that the reading-frame lengths in a random nucleotide sequence are distributed in a negative exponential manner and that there exists an upper limit of about 200 codons in the length of the r...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1986
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323245/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3457379/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.7.2133 |
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