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Origin of eukaryotic introns: a hypothesis, based on codon distribution statistics in genes, and its implications.

A hypothesis for the origin of introns in eukaryotic genes is developed. By computer simulation it was found that the reading-frame lengths in a random nucleotide sequence are distributed in a negative exponential manner and that there exists an upper limit of about 200 codons in the length of the r...

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Pubblicato in:Proc Natl Acad Sci U S A
Autore principale: Senapathy, P
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1986
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323245/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3457379/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.7.2133
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