Mechanistic Contribution of Ubiquitous 15-Lipoxygenase-1 Expression Loss in Cancer Cells to Terminal Cell Differentiation Evasion

Loss of terminal cell differentiation promotes tumorigenesis. 15-LOX-1 contributes to terminal cell differentiation in normal cells. The mechanistic significance of 15-LOX-1 expression loss in human cancers to terminal cell differentiation suppression is unknown. In a screen of 128 cancer cell lines...

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Hlavní autoři: Moussalli, Micheline J., Wu, Yuanqing, Zuo, Xiangsheng, Yang, Xiu L., Wistuba, Ignacio Ivan, Raso, Maria G., Morris, Jeffrey S., Bowser, Jessica L., Minna, John D., Lotan, Reuben, Shureiqi, Imad
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232310/
https://ncbi.nlm.nih.gov/pubmed/21881028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0280
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