15-LOX-1 suppression of hypoxia-induced metastatic phenotype and HIF-1α expression in human colon cancer cells

The expression of 15-lipoxygenase-1 (15-LOX-1) is downregulated in colon cancer and other major cancers, and 15-LOX-1 reexpression in cancer cells suppresses colonic tumorigenesis. Various lines of evidence indicate that 15-LOX-1 expression suppresses premetastatic stages of colonic tumorigenesis; n...

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Bibliografske podrobnosti
Main Authors: Wu, Yuanqing, Mao, Fei, Zuo, Xiangsheng, Moussalli, Micheline J, Elias, Elias, Xu, Weiguo, Shureiqi, Imad
Format: Artigo
Jezik:Inglês
Izdano: BlackWell Publishing Ltd 2014
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101738/
https://ncbi.nlm.nih.gov/pubmed/24634093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.222
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