Prognostic relevance of RUNX1 mutations in T-cell acute lymphoblastic leukemia

The runt-related transcription factor 1, RUNX1, is crucial in the development of myeloid and lymphoid cell lineages and has been reported to be mutated in myeloid malignancies in approximately 30% of cases. In this study, the mutational status of RUNX1 was investigated in 128 acute lymphoblastic leu...

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Bibliographic Details
Main Authors: Grossmann, Vera, Kern, Wolfgang, Harbich, Stefan, Alpermann, Tamara, Jeromin, Sabine, Schnittger, Susanne, Haferlach, Claudia, Haferlach, Torsten, Kohlmann, Alexander
Format: Artigo
Language:Inglês
Published: Ferrata Storti Foundation 2011
Subjects:
Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232273/
https://ncbi.nlm.nih.gov/pubmed/21828118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.043919
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