CDKN1B, encoding the cyclin-dependent kinase inhibitor 1B (p27), is located in the minimally deleted region of 12p abnormalities in myeloid malignancies and its low expression is a favorable prognostic marker in acute myeloid leukemia

BACKGROUND: Alterations of the short arm of chromosome 12 (12p) occur in various hematologic malignancies and ETV6 and CDKN1B, which are located on 12p, have been implicated as leukemogenic genes of interest. DESIGN AND METHODS: We selected seven patients with myeloid malignancies and small 12p dele...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Haferlach, Claudia, Bacher, Ulrike, Kohlmann, Alexander, Schindela, Sonja, Alpermann, Tamara, Kern, Wolfgang, Schnittger, Susanne, Haferlach, Torsten
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ferrata Storti Foundation 2011
Schlagworte:
Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105644/
https://ncbi.nlm.nih.gov/pubmed/21422114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.035584
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge