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Crystallization and preliminary X-ray diffraction analysis of Val57 mutants of the amyloidogenic protein human cystatin C

Human cystatin C (hCC) is a low-molecular-mass protein (120 amino-acid residues, 13 343 Da) found in all nucleated cells. Its main physiological role is regulation of the activity of cysteine proteases. Biologically active hCC is a monomeric protein, but all crystallization efforts have resulted in...

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Bibliografiska uppgifter
Huvudupphovsmän: Orlikowska, Marta, Jankowska, Elzbieta, Borek, Dominika, Otwinowski, Zbyszek, Skowron, Piotr, Szymańska, Aneta
Materialtyp: Artigo
Språk:Inglês
Publicerad: International Union of Crystallography 2011
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232151/
https://ncbi.nlm.nih.gov/pubmed/22139178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111039741
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