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Overexpression, crystallization and preliminary X-­ray crystallographic analysis of shikimate dehydrogenase from Archaeoglobus fulgidus

Shikimate dehydrogenase (SDH), which catalyses the NADPH-dependent reduction of 3-dehydroshikimate to shikimate in the shikimate pathway, is an attractive target for the development of herbicides and antimicrobial agents. Previous structural studies have shown that SDH exists in two conformations, a...

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Autor principal: Lee, Hyung Ho
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232138/
https://ncbi.nlm.nih.gov/pubmed/22139165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111041194
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