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Overexpression, crystallization, and preliminary X-ray crystallographic analysis of shikimate dehydrogenase from Thermotoga maritima

Shikimate dehydrogenase (SDH), which catalyses the NADPH-dependent reduction of 3-dehydroshikimate to shikimate in the shikimate pathway, is an attractive target for the development of herbicides and antimicrobial agents. Previous structural studies showed that SDH exists in two conformations, an op...

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Detalhes bibliográficos
Autor principal: Lee, Hyung Ho
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144806/
https://ncbi.nlm.nih.gov/pubmed/21795804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111019877
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