Pharmacokinetics of dl-praeruptorin A after single-dose intravenous administration to rats with liver cirrhosis

BACKGROUND AND THE PURPOSE OF THE STUDY: As a novel drug in the treatment of cardiac diseases, dl-praeruptorin A (Pd-Ia) is the major active component of traditional herbal medicine Peucedanum praeruptorum Dunn and is metabolized primarily via cytochrome P450 isozymes (CYP) 3A1 and 3A2 in rats. In t...

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Hlavní autoři: Zhang, Z, Liang, XF, Su, MQ, Liang, Q, Li, LP, Zhang, XH, Wang, XM, Zhu, X
Médium: Artigo
Jazyk:Inglês
Vydáno: Tehran University of Medical Sciences 2011
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232105/
https://ncbi.nlm.nih.gov/pubmed/22615659
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