Safety, tolerance, and pharmacokinetic evaluation of cefepime after administration of single intravenous doses.
In this double-blind, single-dose phase I study, the safety and tolerance of cefepime were assessed in 24 healthy male subjects, with ceftazidime as the control drug. Four subjects in each of the six dose groups (62.5, 125, 250, 500, 1,000, or 2,000 mg as a 30-min intravenous infusion) received each...
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| Publicado no: | Antimicrob Agents Chemother |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171768/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2203303/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.6.1118 |
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