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Investigation of formulation variables affecting the properties of lamotrigine nanosuspension using fractional factorial design
BACKGROUND AND THE PURPOSE OF THE STUDY: Lamotrigine (LMG) undergoes extensive hepatic metabolism upon oral administration and its absorption is affected in the presence of food. This study was aimed to develop nanosuspension of LMG and investigate its formulation characteristics using L(9) orthogon...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Tehran University of Medical Sciences
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3232085/ https://ncbi.nlm.nih.gov/pubmed/22615586 |
| タグ: |
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