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Influence of Formulation Factors on Tablet Formulations with Liquid Permeation Enhancer Using Factorial Design

For a drug with low bioavailability, a matrix tablet with liquid permeation enhancer (Labrasol®) was formulated. Factorial design was used to evaluate the effect of three formulation factors: drug percentage, polymer type (Methocel® K100M or Eudragit® L 100-55), and tablet binder percentage (Plasdon...

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Detaylı Bibliyografya
Asıl Yazarlar: Bejugam, Naveen K., Parish, Helen J., Shankar, Gita N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer US 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799611/
https://ncbi.nlm.nih.gov/pubmed/19957114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9345-8
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