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Influence of Formulation Factors on Tablet Formulations with Liquid Permeation Enhancer Using Factorial Design
For a drug with low bioavailability, a matrix tablet with liquid permeation enhancer (Labrasol®) was formulated. Factorial design was used to evaluate the effect of three formulation factors: drug percentage, polymer type (Methocel® K100M or Eudragit® L 100-55), and tablet binder percentage (Plasdon...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer US
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2799611/ https://ncbi.nlm.nih.gov/pubmed/19957114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9345-8 |
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