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IFN-αβ and self-MHC divert CD8 T cells into a distinct differentiation pathway characterized by rapid acquisition of effector functions
Non-virus-specific bystander CD8 T cells bathe in an inflammatory environment during viral infections. To determine if bystander CD8 T cells are affected by these environments, we examined P14, HY, and OT-I TCR transgenic CD8 T cells sensitized in vivo by IFN-αβ-inducing viral infections or by poly(...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3232037/ https://ncbi.nlm.nih.gov/pubmed/20592282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001140 |
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