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Defective Metabolic Signaling in Adenylate Kinase AK1 Gene Knock-out Hearts Compromises Post-ischemic Coronary Reflow

Matching blood flow to myocardial energy demand is vital for heart performance and recovery following ischemia. The molecular mechanisms responsible for transduction of myocardial energetic signals into reactive vasodilatation are, however, elusive. Adenylate kinase, associated with AMP signaling, i...

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Detalhes bibliográficos
Main Authors: Dzeja, Petras P., Bast, Peter, Pucar, Darko, Wieringa, Be, Terzic, Andre
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232003/
https://ncbi.nlm.nih.gov/pubmed/17704060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M705268200
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