Chronic Antagonism of the Mineralocorticoid Receptor Ameliorates Hypertension and End Organ Damage in a Rodent Model of Salt-Sensitive Hypertension

We investigated the effects of chronic mineralocorticoid receptor blockade with eplerenone on the development and progression of hypertension and end organ damage in Dahl salt-sensitive rats. Eplerenone significantly attenuated the progressive rise in systolic blood pressure (SBP) (204 ± 3 vs. 179±3...

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Bibliografski detalji
Glavni autori: Zhou, Xiaoyan, Crook, Martin F, Sharif-Rodriguez, Wanda, Zhu, Yonghua, Ruben, Zadok, Pan, Yi, Urosevic-Price, Olga, Wang, Li, Flattery, Amy M, Forrest, Gail, Szeto, Daphne, Zhao, Huawei, Roy, Sophie, Forrest, Michael J
Format: Artigo
Jezik:Inglês
Izdano: Informa Healthcare 2011
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Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3231850/
https://ncbi.nlm.nih.gov/pubmed/21950654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10641963.2011.566956
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