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Mineralocorticoid receptor antagonism attenuates experimental pulmonary hypertension
Mineralocorticoid receptor (MR) activation stimulates systemic vascular and left ventricular remodeling. We hypothesized that MR contributes to pulmonary vascular and right ventricular (RV) remodeling of pulmonary hypertension (PH). We evaluated the efficacy of MR antagonism by spironolactone in two...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Physiological Society
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3652061/ https://ncbi.nlm.nih.gov/pubmed/23457185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00300.2012 |
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